The collision happened along the 5 Freeway Saturday morning, and it appears fog may have played a role.
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Police said 35 vehicles - including 18 big rigs - crashed into each other, causing a major chain-reaction collision.
The California Highway Patrol closed southbound lanes of the 5 Freeway between Millux Road and Old River Road for several hours. All lanes were reopened by 8 a.m. Sunday.
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