Police say the crash happened at about 7 pm on Saturday in the area of Bullard and Temperance.
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Bullard was shut down for hours in both directions as police investigate.
The pedestrian, 57-year-old Sidney Carpenter died of his injuries at the scene of the crash.
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The driver of the vehicle stayed behind and was cooperating with police.
Officers say Carpenter was not crossing the street at a marked crosswalk.