The former world champion will be fighting on March 25 against former lightweight world champion Richard "RC" Commey at the Save Mart Center.
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Along with Ramirez's fight will be a world title unification bout between WBA minimumweight world champion Seniesa "Super Bad" Estrada and WBC world champion Tina Rupprecht.
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Both fights will be broadcasted live on ESPN, ESPN deportes and ESPN+.
Tickets start at $29 and will go on sale Friday, Jan. 13 at 10 a.m. on Ticketmaster and at the Save Mart Center's Box office.