The crash happened around 7:20 p.m. in the area of Bethel and Almond avenues.
The Sanger Police Department says the juveniles were crossing the street when they were struck by a driver who did not see them.
The ages of the victims are currently unclear.
The driver stayed at the scene following the crash.
Officials have not yet released any other details.
The crash happened just a block away from where 10-year-old Jameson Doyle was killed after being hit by a truck last year.
Bethel is expected to be closed between Almond and Annadale for at least another hour.