The shooting happened at Pleasant and Fedora Avenues just after 2 am Thursday.
Police found a 22-year-old man and 28-year-old man in the street near an apartment complex.
The 22-year-old was declared dead at the scene.
The 28-year-old was rushed to the hospital in critical condition.
No information on what led up to the shooting has been released.
Anyone with more information is asked to contact Fresno police.