Halle Bailey said she was thrilled to dive into the title role and the gravity of the moment was not lost on the young star.
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"This moment means everything to me. I feel so inspired and grateful and honored," said Bailey.
Melissa McCarthy takes over the villainous role of the sea witch Ursula, made famous in the animated movie by Pat Carroll.
"She is glamorous, she's a bygone day of glamour and a broad and not afraid to speak her mind," said McCarthy. "Not always great decisions. I think she's misunderstood."
Like many of us, Awkwafina, who lends her voice to "Scuttle," has watched the original 1989 animated film over and over.
"I was die-hard fan of the original," she said. "One of my favorite scenes was Dinglehopper with Scuttle. It's just an honor."
This re-imagining of the animated Disney classic brought out some curious celebrities who didn't want to wait for opening day to see it.
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That includes Jodi Benson, the actress who voiced Ariel in the original film.
"This is a dream to be here 37 years later, really," said Benson. "Our little film that changed animation all those years ago. It's magical."
"The Little Mermaid" hits theaters Friday, May 26.
Disney is the parent company of this ABC station.