Sony Pictures Entertainment released the first movie trailer Monday, starring Hanks.
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It shows Hanks dressed as the children's television host.
"It only takes one person to inspire a world of kindness," posted Sony.
The official trailer prompted a lot of emotional reactions from fans.
"This alone makes me want to cry with joy. I'm already so moved," one person wrote.
Another person added, "what a great way to start the week. Hope everyone is smiling right now."
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The movie trailer ends with a touching scene. It shows schoolchildren singing to Mr. Rogers on the subway.
"Hey Mr. Rogers, It's a beautiful day in this neighborhood. A beautiful day for a neighbor. Please, won't you be my neighbor."
"Mister Rogers' Neighborhood" aired from 1968 until 2001.
Rogers died in 2003.
"A Beautiful Day in the Neighborhood" is set to be released Nov. 22, 2019.