It happened just before 4 am on Avenue 352 near Road 36, south of Traver.
[Ads /]
The California Highway Patrol said the driver of a Volkswagen Jetta hit a spray rig being towed by a tractor.
The driver suffered major injuries and was transported to Kaweah Health Medical Center.
The person driving the tractor remained at the scene. It's unclear if they were injured.
[Ads /]
Officers are working to determine what led up to the crash.