Officials responded to reports of a Dodge Challenger traveling north in the southbound lanes near the Manning Avenue exit around 1:30 am.
The CHP said the driver was going about 55 miles per hour. Officers were able to stop him on the highway's center median near the Merced Street off-ramp.
A beer bottle was seen in the car. There was also damage to the back of the vehicle, but the driver said it was from a previous incident.
He was taken into custody accused of driving under the influence.
No one was hurt.