Two workers were killed and one was seriously injured in what officials termed a "possible explosion" at Delta Air Lines' Atlanta Technical Operations Maintenance facility at Hartsfield-Jackson Atlanta International Airport, according to Delta TechOps and first responders.
Delta TechOps said the Tuesday morning accident took place at its wheel and brake shop.
Responders to the "possible explosion" found "three Delta employees on the floor," and the medics said they tried to control "major bleeding," according to the Atlanta Fire and Rescue Department's incident report.
An employee reported hearing an explosion and seeing workers fleeing, the incident report said.
"I realized they were running to get help. I walked toward where the explosion occurred and saw a body lying face down, not moving, with blood all around," the worker told officials, according to the incident report.
Delta said the accident involved a tire and components within the tire. The wheel was not attached to an airplane or near an airplane at the time of the accident, according to Delta.
The wheels were being "disassembled for maintenance" and not attached to an aircraft, according to investigators.
The incident had no impact on airport operations, according to airport officials.
The federal Occupational Safety and Health Administration said it opened an investigation.
Delta said it's "working with local authorities and conducting a full investigation to determine what happened."
The airline added it's "heartbroken" and "grateful for the quick action of first responders and medical teams on site."
The workers killed in the incident were identified as Mirko Marweg, 58, and Luis Aldarondo, 37, according to the Clayton County Medical Examiner's Office. The third employee, who hasn't immediately been identified, remains hospitalized, according to officials.
"We are extending our full support to their families at this difficult time and conducting an investigation to determine what happened," John Laughter, executive vice president, chief of operations and president of Delta TechOps, said in a statement. "This news is heartbreaking for all of us. [Employee assistance program] resources will be onsite at the [Atlanta Technical Operations Maintenance facility] to support our teams as long as needed."
Atlanta Mayor Andre Dickens said, "I offer my deepest condolences to the family and loved ones of the deceased Delta employees. My thoughts are also with those who were injured, and I hope for their swift and full recovery."
Atlanta airport officials also offered their condolences.
ABC News' Sam Sweeney contributed to this report.